概述
MatwingsVenus™ 是面向高校科研工作者、企业研发人员、医护工作者与生物爱好者，打造的轻量级 AI 生物设计 + 湿实验验证 + 专家协同的研发闭环平台。
数据积累：整合 NCBI、UniProt、MGnify 等各大数据库百亿条标注序列数据集。
Agent能力：整合智能对话、蛋白序列分析、定向突变设计、酶挖掘、从头设计、结构预测与数据库检索等核心功能，让复杂的生物信息学任务以对话方式完成。
湿实验验证：平台支持一键下单基因合成、蛋白表达验证、蛋白纯化等服务。
专家协同：在蛋白质设计全流程中，您可随时发起专家咨询。我们将协调领域专家，及时解答您的问题，评估 AI 模型的设计结果，并为设计方案提供专业判断、优化建议与深入见解。
智能体核心研发流
模拟人类专家的思考过程，自动化执行复杂的生物信息学任务。
智能助手
主动式AI助手，自然语言即可帮助用户解决科研问题，加速科学发现。完成结构预测、专利检索、文献检索等任务，支持直连 PubMed、PDB、UniProt 等多数据库。
蛋白改造
AI 定向进化领域的全球第一技术：支持多轮活性提升，已在 30 余个产业项目中验证效果。平台可进行单点饱和突变预测，或结合用户的湿实验数据进行多点突变预测，并识别功能位点进行风险分析和理化性质预测。
蛋白发现
从数亿序列中快速定位目标蛋白，依托零样本预测能力、跨越序列限制通过结构搜索功能相似的蛋白。
海量蛋白质数据库检索
连接百亿级蛋白质 序列与结构数据库
核心检索技术
亮点
先进模型能力
百亿级参数-Venus-系列模型，具备世界领先的零样本预测、多轮进化、功能预测能力。
海量数据库支撑
海量私有极端环境蛋白质序列数据集，十余专业数据库，信息覆盖全面。
可验证的预测效果
蛋白进化已在 30+ 产业项目中成功交付，蛋白发现能突破序列相似性低的限制找到功能相似酶。
极致轻量化体验
所有专业能力均可通过一句话触发，无需生信背景或复杂操作，让科研者专注科学问题本身。
新闻公告
蛋白质工程：在失败的废墟上，我们学会了设计生命
蛋白质工程的历程并非简单的从“随机试错”到“AI智能设计”的线性胜利，而是一部充满失败与意外发现的探险记。AI如蛋白质语言模型的出现，不仅加速了探索，更让我们从“改造自然”跨入“平行创造”的新纪元，成为生命源代码的合著者。
智能科研平台迭代：打破实验室孤岛，打造科研超级连接器
科研界正经历从“孤立工具堆砌”到“智能协同共生”的变革，AI智能体协作平台打破数据孤岛，让科学家专注核心问题而非工具适配。垂直平台如MatwingsVenus 已实现蛋白质研发全流程自主闭环，未来科研将是AI智囊团24小时在线协同的创新生态。标准统一将加速孤岛盆景迈向全域联动的产业全景。
蛋白质序列：从解读到设计，AI如何重塑生命密码？
今天，蛋白质序列的设计正从一种高度依赖直觉和运气的手艺，迅速演变为以数据和模型驱动的可预测工程。从序列出发，重塑蛋白质功能，赋能生物制造，是人类迈向绿色、可持续未来的重要技术引擎。
学术发表
VenusX: Unlocking Fine-Grained Functional Understanding of Proteins
ICLR, 2026.
2026-01-26
Fast and Interpretable Protein Substructure Alignment via Optimal Transport
ICLR, 2026.
2026-01-26
Venus-MAXWELL: Efficient Learning of Protein-Mutation Stability Landscapes using Protein Language Models
NeurIPS, 2025
2025-09-19
STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces
Proceedings of the National Academy of Sciences, 2025
2025-08-26
From high-throughput evaluation to wet-lab studies: advancing mutation effect prediction with a retrieval-enhanced model
ISMB/ECCB, 2025.
2025-07-15
Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases
Nature Communications, 2025
2025-07-05
VenusFactory: An Integrated System for Protein Engineering with Data Retrieval and Language Model Fine-Tuning
ACL Demo, 2025.
2025-07-01
A Deep Retrieval-Enhanced Meta-Learning Framework for Enzyme Optimum pH Prediction
J. Chem. Inf. Model, 2025,
2025-03-24
VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data
Acta Pharmaceutica Sinica B, 2025
2025-03-14
Entropy-driven zero-shot deep learning model selection for viral proteins
Physical Review Research, 2025,
2025-02-28
AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
Elife, 2025,
2025-02-19
Immunogenicity Prediction with Dual Attention Enables Vaccine Target Selection
ICLR, 2025.
2025-01-23
PROTSOLM: Protein Solubility Prediction with Multi-modal Features
IEEE BIBM, 2024.
2025-01-10
Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion
IEEE BIBM, 2024.
2025-01-10
Protein Representation Learning with Sequence Information Embedding: Does it Always Lead to a Better Performance?
IEEE BIBM, 2024.
2025-01-10
VenusX: Unlocking Fine-Grained Functional Understanding of Proteins
ICLR, 2026.
2026-01-26
Fast and Interpretable Protein Substructure Alignment via Optimal Transport
ICLR, 2026.
2026-01-26
Venus-MAXWELL: Efficient Learning of Protein-Mutation Stability Landscapes using Protein Language Models
NeurIPS, 2025
2025-09-19
STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces
Proceedings of the National Academy of Sciences, 2025
2025-08-26
From high-throughput evaluation to wet-lab studies: advancing mutation effect prediction with a retrieval-enhanced model
ISMB/ECCB, 2025.
2025-07-15
Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases
Nature Communications, 2025
2025-07-05
VenusFactory: An Integrated System for Protein Engineering with Data Retrieval and Language Model Fine-Tuning
ACL Demo, 2025.
2025-07-01
A Deep Retrieval-Enhanced Meta-Learning Framework for Enzyme Optimum pH Prediction
J. Chem. Inf. Model, 2025,
2025-03-24
VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data
Acta Pharmaceutica Sinica B, 2025
2025-03-14
Entropy-driven zero-shot deep learning model selection for viral proteins
Physical Review Research, 2025,
2025-02-28
AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
Elife, 2025,
2025-02-19
Immunogenicity Prediction with Dual Attention Enables Vaccine Target Selection
ICLR, 2025.
2025-01-23
PROTSOLM: Protein Solubility Prediction with Multi-modal Features
IEEE BIBM, 2024.
2025-01-10
Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion
IEEE BIBM, 2024.
2025-01-10
Protein Representation Learning with Sequence Information Embedding: Does it Always Lead to a Better Performance?
IEEE BIBM, 2024.
2025-01-10
